[Search for HHV-8 associated diseases reservoir and spread paths of HHV-8 in Russia]. / Poiski HHV-8-assotsiirovannykh zabolevanii, rezervuara i putei rasprostraneniia HHV-8 v Rossii.
Vopr Virusol
; 49(6): 20-4, 2004.
Article
en Ru
| MEDLINE
| ID: mdl-15597956
Summarized in the paper are study results of human herpesvirus type 8 (HHV-8) and of its association with Kaposi's sarcoma (KS). The data obtained denotes that the share of individuals producing the antibodies to HHV-8 in a majority of studied patients was low and ranged form 0 to 5.5%, which is indicative of a low degree of the virus spread in population. At the same time, a high share of persons with antibodies to HHV-8 was detected among HIV-infected homosexuals (71.4%), kidney recipients (26.0%) and among AIDS-KS patients (78.6%). It was also unexpectedly high among patients with T- and B-cell lymphomas (50%), encephalopathy (27.3%) and with stomach cancer (41.8%): the appropriate parameters were 7-12-fold higher versus healthy subjects. The HHV-8 markers, i.e. virus specific antibodies and/or nucleotide sequences of the virus, were detected in blood serum and ejaculate of a significant number of patients with different pathologies of the prostate. Such detection of viral markers in the above categories of patients is suggestive of that sexual contacts with such patients are decisive for the HHV-8 spread in population.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Reservorios de Enfermedades
/
Infecciones por Herpesviridae
/
Herpesvirus Humano 8
/
Anticuerpos Antivirales
Tipo de estudio:
Etiology_studies
/
Risk_factors_studies
Límite:
Female
/
Humans
/
Male
País/Región como asunto:
Asia
/
Europa
Idioma:
Ru
Revista:
Vopr Virusol
Año:
2004
Tipo del documento:
Article
Pais de publicación:
Rusia