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Value of health-related quality of life to predict disability course in multiple sclerosis.
Visschedijk, M A J; Uitdehaag, B M J; Klein, M; van der Ploeg, E; Collette, E H; Vleugels, L; Pfennings, L E M A; Hoogervorst, E L J; van der Ploeg, H M; Polman, C H.
Afiliación
  • Visschedijk MA; Department of Medical Psychology, VU University Medical Center, Van der Boechorststraat 7, 1081 BT Amsterdam, The Netherlands maj.visschedijk@vumc.nl
Neurology ; 63(11): 2046-50, 2004 Dec 14.
Article en En | MEDLINE | ID: mdl-15596748
OBJECTIVE: To determine the value of health-related quality of life (HRQoL) to predict change in disability status in patients with multiple sclerosis (MS). METHODS: Over a 5-year period, data were collected on HRQoL (Medical Outcomes Study Short Form-36 Health Survey) and disability status (Expanded Disability Status Scale) from a heterogeneous group of 81 Dutch-speaking patients with MS. RESULTS: Multivariate logistic regression analysis showed that HRQoL in the domains of Physical Functioning and Role-Physical Functioning is a significant predictor of change in disability status. CONCLUSIONS: A patient's subjectively perceived health-related quality of life may not be only a clinically and psychosocially meaningful outcome per se but may also be a predictor of objective outcomes such as change in disability status over a substantial period of time.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Calidad de Vida / Esclerosis Múltiple Tipo de estudio: Evaluation_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Aspecto: Patient_preference Límite: Adult / Aged / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: Neurology Año: 2004 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Estados Unidos
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Calidad de Vida / Esclerosis Múltiple Tipo de estudio: Evaluation_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Aspecto: Patient_preference Límite: Adult / Aged / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: Neurology Año: 2004 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Estados Unidos