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Primary tumours of the optic nerve and its sheath.
Miller, N R.
Afiliación
  • Miller NR; Wilmer Eye Institute, Johns Hopkins Hospital, Baltimore, MD 21287, USA.
Eye (Lond) ; 18(11): 1026-37, 2004 Nov.
Article en En | MEDLINE | ID: mdl-15534587
PURPOSE: To describe the clinical, neuroimaging, and pathologic features of primary tumours of the optic nerve and its sheath. METHODS: Review of published cases and personal series. RESULTS: The most common primary tumour of the optic nerve is the benign glioma. This low-grade astrocytoma usually can be followed without intervention. Progression of visual symptoms and signs may necessitate either surgery to remove the tumour or radiation therapy. The most common tumour of the optic nerve sheath is the meningioma. The optimum treatment for this lesion is stereotactic or three-dimensional conformal fractionated radiation therapy, which generally results in stabilization or improvement in vision. A variety of other primary tumours may mimic, in both manifestations and imaging appearance, the more common glioma or meningioma. In such cases, the correct diagnosis may not be made until a biopsy is performed or the nerve is removed. CONCLUSION: Primary tumours of the optic nerve and its sheath are not uncommon. Diagnosis can often but not always be made by the results of a complete examination combined with imaging studies, particularly CT scanning and MR imaging. Management depends on the presumed or histologically verified nature of the tumour.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias del Nervio Óptico Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Eye (Lond) Asunto de la revista: OFTALMOLOGIA Año: 2004 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias del Nervio Óptico Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Eye (Lond) Asunto de la revista: OFTALMOLOGIA Año: 2004 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido