Phospholipid composition of myocardium in children with normoxemic and hypoxemic congenital heart diseases.
Physiol Res
; 53(5): 557-60, 2004.
Article
en En
| MEDLINE
| ID: mdl-15479135
Samples of myocardial tissue were obtained during cardiac surgery from children operated for different types of normoxemic and hypoxemic congenital heart diseases. The phospholipid composition was analyzed by thin layer chromatography. The concentration of total phospholipids (PL), phosphatidylcholine and phosphatidylethanolamine (PE) was found lower in atrial tissue of both normoxemic and hypoxemic groups in comparison with the ventricles. When comparing the difference between hypoxemic and normoxemic defects, hypoxemia was found to increase the concentration of total PL, PE and phosphatidylserine in ventricles and total PL and PE in the atria. The increased level of particular phospholipid species may represent adaptive mechanisms to hypoxemia in children with congenital heart diseases.
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Fosfolípidos
/
Atrios Cardíacos
/
Cardiopatías Congénitas
/
Ventrículos Cardíacos
/
Hipoxia
/
Miocardio
Tipo de estudio:
Clinical_trials
Límite:
Child
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Physiol Res
Asunto de la revista:
FISIOLOGIA
Año:
2004
Tipo del documento:
Article
País de afiliación:
República Checa
Pais de publicación:
República Checa