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Lessons from HIV and hepatitis viruses.
Sacks, S L; Griffiths, P D; Corey, L; Cohen, C; Cunningham, A; Dusheiko, G M; Self, S; Spruance, S; Stanberry, L R; Wald, A; Whitley, R J.
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  • Sacks SL; Viridae, Vancouver, Canada.
Antiviral Res ; 63 Suppl 1: S11-8, 2004 Aug.
Article en En | MEDLINE | ID: mdl-15450381
Surrogate markers are an important component in the process of investigating management and prevention strategies, and for increasing understanding of viral diseases. The importance of surrogate markers and applied statistical models is particularly true for HIV. For HIV infection, the development of such methods provides new approaches for evaluation of HIV therapies and vaccines, and for the study of HIV transmission and its pathogenesis. The complex natural history of hepatitis B infection demonstrates that viral load is not the only predictor of transmission of this virus; for hepatitis C infection, viral load per se is not a prognostic factor for disease progression, but cumulative viral load may affect the outcome, and therapy is aimed at eliminating active viral replication.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por VIH / Virus de la Hepatitis B / VIH / Hepatitis C / Hepacivirus / Hepatitis B Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Antiviral Res Año: 2004 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Países Bajos
Buscar en Google
Añadir a Mi BVS
Imprimir
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PubMed Links

Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por VIH / Virus de la Hepatitis B / VIH / Hepatitis C / Hepacivirus / Hepatitis B Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Antiviral Res Año: 2004 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Países Bajos