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Epidemiology, clinical and economic burden, and natural history of chronic obstructive pulmonary disease and asthma.
Skrepnek, Grant H; Skrepnek, Stan V.
Afiliación
  • Skrepnek GH; Department of Pharmaceutical Sciences, and Center for Health Outcomes and Pharmacoeconomics Research, University of Arizonia, College of Pharmacy, Tucson, USA.
Am J Manag Care ; 10(5 Suppl): S129-38, 2004 Jul.
Article en En | MEDLINE | ID: mdl-15354678
Chronic obstructive pulmonary disease (COPD) and asthma are conditions that exact a tremendous toll on patients, providers, and society. The substantial increase in the prevalence of both conditions in recent decades has generated sizable concern from both domestic and global perspectives. The underlying characteristics of both conditions involve inflammation of the respiratory tract, although the specific nature and reversibility of these processes differ according to each illness. Within the context of disease management, acute exacerbations are important clinical events that contribute to an increase in morbidity and mortality, and may occur in any patient suffering from the disease. Because these conditions are highly important to clinical practice and healthcare systems, this article will highlight key aspects of epidemiology, burden of illness, and clinical presentation of COPD and asthma. A review of the definition, classification, and natural history is also offered, emphasizing the role of acute exacerbations. In general, the natural history of both COPD and asthma is highly variable and not precisely defined because of their heterogeneous clinical courses. Continued inquiry concerning the epidemiology, etiology, classification, and prognosis of each condition and related exacerbations may offer clinicians improved decision-making information to optimize interventions for affected patient populations.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Asma / Costo de Enfermedad / Enfermedad Pulmonar Obstructiva Crónica Tipo de estudio: Health_economic_evaluation / Prognostic_studies / Risk_factors_studies / Screening_studies Límite: Humans País/Región como asunto: America do norte Idioma: En Revista: Am J Manag Care Asunto de la revista: SERVICOS DE SAUDE Año: 2004 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Asma / Costo de Enfermedad / Enfermedad Pulmonar Obstructiva Crónica Tipo de estudio: Health_economic_evaluation / Prognostic_studies / Risk_factors_studies / Screening_studies Límite: Humans País/Región como asunto: America do norte Idioma: En Revista: Am J Manag Care Asunto de la revista: SERVICOS DE SAUDE Año: 2004 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos