[Cytotoxicity of chymopapain combined with pingyangmycin on mouse hepatoma cell line hepa-6].
Zhong Yao Cai
; 27(4): 267-9, 2004 Apr.
Article
en Zh
| MEDLINE
| ID: mdl-15307684
OBJECTIVE: To observe the cytotoxicity of chymopapain combined with pingyangmycin (PYM) on mouse hepatoma cell line hapa-6 in vitro. METHOD: MTT method. RESULTS: Chymopapain showed cytotoxicities to hepa-6 (IC50 is about 1200 microg/ml) and had concentration dependency. Cooperation effect was showed when three different concentration chymopapain combined with PYM during 48 hours. It accorded with the change of enzyme activity of chymopapain in saline water. Cooperation effect was showed again when adding chymopapin for the second time at 48 hours. CONCLUSION: Chymopapain has cytotoxicity on hepa-6 in vitro. Cooperation effect was showed when chymopapin was combined with PYM.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Bleomicina
/
Medicamentos Herbarios Chinos
/
Quimopapaína
/
Neoplasias Hepáticas Experimentales
Límite:
Animals
Idioma:
Zh
Revista:
Zhong Yao Cai
Asunto de la revista:
TERAPIAS COMPLEMENTARES
Año:
2004
Tipo del documento:
Article
Pais de publicación:
China