An acute toxic neuropathy caused by organo-phosphate poisoning in hens.

Varsik, P; Pechan, I; Buranova, D; Kucera, P

Varsik, P; Pechan, I; Buranova, D; Kucera, P.

Afiliación

Varsik P; 1st Department of Neurology, Faculty of Medicine, Comenius University, Bratislava, Slovakia. neurologia@faneba.sk

Bratisl Lek Listy ; 105(3): 91-4, 2004.

Article en En | MEDLINE | ID: mdl-15253525

RESUMEN

OBJECTIVE: Organophosphorus compounds can induce an acute toxic peripheral neuropathy. In hens, the acute peripheral neuropathy was induced by poisoning with organo-phosphorus compound (OPC)--tri-ortho-cresyl phosphate (TOCP). METHODS: In the course of an acute TOCP-induced toxic neuropathy in hens the activity of following enzymes was analysed: asparaginase, glutaminase, glutamat-dehydrogenase, AMP and adenosine deaminases and 5'nucleotidase; ALT (SGPT), AST (SGOT) and proteins levels were estimated. RESULTS: A decrease in activity of all analysed enzymes was observed; the amount of proteins was increased. CONCLUSION: The biochemical changes display the slowing or stoppage in axonal transport of proteins. The disturbance of axoplasmic flow and the axonal demyelination may be considered as an attribute of peripheral neuropathy. (Tab. 1, Fig. 1, Ref. 32.).

Asunto(s)

Síndromes de Neurotoxicidad/enzimología; Tritolilfosfatos/envenenamiento; Enfermedad Aguda; Animales; Pollos; Femenino; Síndromes de Neurotoxicidad/diagnóstico; Síndromes de Neurotoxicidad/etiología; Enfermedades del Sistema Nervioso Periférico/inducido químicamente

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tritolilfosfatos / Síndromes de Neurotoxicidad Tipo de estudio: Diagnostic_studies / Etiology_studies Límite: Animals Idioma: En Revista: Bratisl Lek Listy Año: 2004 Tipo del documento: Article País de afiliación: Eslovaquia Pais de publicación: Eslovaquia

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