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Linezolid-induced bradycardia: a case report.
Tartarone, Alfredo; Gallucci, Giuseppina; Iodice, Giovanni; Romano, Giampiero; Coccaro, Mariarosa; Vigliotti, Maria Luigia; Mele, Giuseppe; Matera, Rosella; Di Renzo, Nicola.
Afiliación
  • Tartarone A; Division of Medical Oncology and Haematology, Centro di Riferimento Oncologico della Basilicata, Strada Provinciale No. 8, 85028 Rionero in Vulture (PZ), Italy. tarta1@virgilio.it
Int J Antimicrob Agents ; 23(4): 412-3, 2004 Apr.
Article en En | MEDLINE | ID: mdl-15081095
We report an episode of severe bradycardia that occurred in a 49-year-old woman with fever and malignant jaundice during antibiotic therapy with linezolid, a new oxazolidinone with activity against Gram-positive cocci. In our case, the strict temporal dependence between bradycardia and linezolid therapy seems to provide strong evidence for a causal relationship. To our knowledge, this is the first report of linezolid-induced bradycardia. This adverse event confirms that the new antibiotic linezolid should be administered with caution in patient with jaundice and hepatic insufficiency.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Bradicardia / Oxazolidinonas / Acetamidas / Antiinfecciosos Límite: Female / Humans / Middle aged Idioma: En Revista: Int J Antimicrob Agents Año: 2004 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Países Bajos
Buscar en Google
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PubMed Links

Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Bradicardia / Oxazolidinonas / Acetamidas / Antiinfecciosos Límite: Female / Humans / Middle aged Idioma: En Revista: Int J Antimicrob Agents Año: 2004 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Países Bajos