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[Synthesis and immunostimulating activity of cysteine-containing glycopeptide derivatives of glycyrrhizic acid]. / Sintez i immunostimuliruiushchaia aktivnost' tsisteinsoderzhashchikh glikopeptidnykh proizvodnykh glitsirrizinovoi kisloty.
Kondratenko, R M; Baltina, L A; Vasil'eva, E V; Baltina, L A; Ismagilova, A F; Nasyrov, Kh M; Baschenko, N Zh; Kireeva, R M; Fridman, S M; Tolstikov, G A.
Afiliación
  • Kondratenko RM; Bashkortostan State Medical University, Ufa, Bashkortostan, 450074 Russia.
Bioorg Khim ; 30(1): 61-7, 2004.
Article en Ru | MEDLINE | ID: mdl-15040305
New cysteine-containing derivatives of glycyrrhizic acid were synthesized by its coupling with Cys(Bzl) esters or the Cys(Bzl)-Val-OBu(t) dipeptide by the active ester method (DCC/HOSu) or by Woodward's reagent K. The derivatives with Cys(Bzl) and Cys(Bzl)-Val residues attached to the carbohydrate part of the molecule stimulated the primary immune response and the reaction of delayed-type hypersensitivity in mice at a dose of 2 mg/kg. The English version of the paper: Russian Journal of Bioorganic Chemistry, 2004, vol. 30, no. 1; see also http://www.maik.ru.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Glicopéptidos / Adyuvantes Inmunológicos / Ácido Glicirrínico / Cisteína Idioma: Ru Revista: Bioorg Khim Año: 2004 Tipo del documento: Article Pais de publicación: Rusia
Buscar en Google
Añadir a Mi BVS
Imprimir
XML
PubMed Links

Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Glicopéptidos / Adyuvantes Inmunológicos / Ácido Glicirrínico / Cisteína Idioma: Ru Revista: Bioorg Khim Año: 2004 Tipo del documento: Article Pais de publicación: Rusia