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Microplate and dot immunoassays for the serodiagnosis of tuberculosis.
McDonough, J A; Sada D, E; Sippola, A A; Ferguson, L E; Daniel, T M.
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  • McDonough JA; Department of Medicine, Case Western Reserve University, Cleveland, OH.
J Lab Clin Med ; 120(2): 318-22, 1992 Aug.
Article en En | MEDLINE | ID: mdl-1500829
A simple dot enzyme immunoassay based on the recognition of serum IgG antibody to a 30,000 dalton native antigen purified from culture filtrates of Mycobacterium tuberculosis was developed and compared with a standard plate enzyme-linked immunosorbent assay in the serodiagnosis of tuberculosis. The previously described favorable test characteristics of plate enzyme-linked immunoassay were confirmed; although the dot enzyme immunoassay was promising, it was less satisfactory. Dot enzyme immunoassay may have its most promising use as a screening test for situations of limited technical facilities. Both plate enzyme-linked immunoassay and dot enzyme immunoassay had markedly reduced sensitivities in persons with human immunodeficiency virus infection.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tuberculosis Pulmonar / Inmunoglobulina G / Infecciones por VIH / Seropositividad para VIH Tipo de estudio: Diagnostic_studies / Etiology_studies / Prevalence_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: J Lab Clin Med Año: 1992 Tipo del documento: Article Pais de publicación: Estados Unidos
Buscar en Google
Añadir a Mi BVS
Imprimir
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PubMed Links

Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tuberculosis Pulmonar / Inmunoglobulina G / Infecciones por VIH / Seropositividad para VIH Tipo de estudio: Diagnostic_studies / Etiology_studies / Prevalence_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: J Lab Clin Med Año: 1992 Tipo del documento: Article Pais de publicación: Estados Unidos