[Serum tryptase: marker of occupational anaphylaxis].

Di Giampaolo, L; Toto, E; Travaglini, P; Russi, M; Huang, S H; Boscolo, P; Di Gioacchino, M

[Serum tryptase: marker of occupational anaphylaxis]. / Triptasi: marker dell'anafilassi occupazionale.

Di Giampaolo, L; Toto, E; Travaglini, P; Russi, M; Huang, S H; Boscolo, P; Di Gioacchino, M.

Afiliación

Di Giampaolo L; Dipartimento di Medicina e Scienze dell'Invecchiamento: Sezione di Medicina del Lavoro, Allergologia ed Immunologia Clinica, Università G. d'Annunzio, Chieti, Italy.

G Ital Med Lav Ergon ; 25 Suppl(3): 144-5, 2003.

Article en It | MEDLINE | ID: mdl-14979122

RESUMEN

Tryptase is a protein released by mast cells, which is involved in the enhancement of inflammatory sequences in immune-mediated reactions. According with our experience, some patients having a reaction clinically classified as anaphylaxis, showed high levels of tryptase (> 20 ng/l) but also of serum specific IgE, showing the immune-mediated nature of the reactions. On the other hand workers without specific IgE and with low levels of tryptase probably had developed pseudoallergic (anaphylactoid) reactions. So, tryptase can be used as biomarker of occupational anaphylaxis and appear to be able to make out immune and nonimmune mediated reactions.

Asunto(s)

Anafilaxia/sangre; Enfermedades Profesionales/sangre; Serina Endopeptidasas/sangre; Femenino; Humanos; Masculino; Triptasas

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Serina Endopeptidasas / Anafilaxia / Enfermedades Profesionales Límite: Female / Humans / Male Idioma: It Revista: G Ital Med Lav Ergon Asunto de la revista: MEDICINA OCUPACIONAL Año: 2003 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Italia

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