Ocular and visual side effects of systemic cyclosporine.
Ann Ophthalmol
; 24(12): 465-9, 1992 Dec.
Article
en En
| MEDLINE
| ID: mdl-1485743
In this study, we investigated the ocular and visual side effects of systemic cyclosporine used as an immunosuppressant in 51 renal transplant recipients during the postoperative period. Three different treatment schemes were used. The patients in the first group received cyclosporine and a corticosteroid. The second group was given azathioprine and a corticosteroid. Those in the third group were treated with azathioprine, a corticosteroid, and cyclosporine. Cotton-wool exudates, retinal hemorrhages, and retinal artery branch occlusion were observed only in one patient each in the second group, and these patients were excluded from the statistical evaluation. Macular hyperpigmentation was observed as a new finding in each group, but there was no statistical difference between the groups. The same results were found for cataract; this probably was related to the use of steroids. Trichomegaly, visual hallucinations, and cerebral blindness were not observed by contrast with previous studies. We suggest that systemic cyclosporine does not have significant ocular and visual side effects.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Enfermedades de la Retina
/
Trastornos de la Visión
/
Catarata
/
Trasplante de Riñón
/
Ciclosporina
Tipo de estudio:
Observational_studies
/
Prognostic_studies
Límite:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Ann Ophthalmol
Año:
1992
Tipo del documento:
Article
País de afiliación:
Turquía
Pais de publicación:
Estados Unidos