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Nodular pulmonary vasculitis in a twelve-year-old boy.
Borchers, T; Dirsch, O; Schaper, J; Kreuzfelder, E; Jakob, H; Ratjen, F.
Afiliación
  • Borchers T; Children's Hospital, University of Essen, Essen, Germany. tanja.borchers@uni-essen.de
Pediatr Pulmonol ; 37(2): 181-5, 2004 Feb.
Article en En | MEDLINE | ID: mdl-14730665
A 12-year-old boy presented with left shoulder pain during physical exercise and complained of uncommon sweating and fatigue. Diagnostic evaluation revealed a solitary pulmonary nodule in the left upper lobe. All laboratory values were within normal limits, except for an elevated level of antineutrophil cytoplasmic antibodies directed against myeloperoxidase (p-ANCA). Surgery was performed, and pathological examination showed a localized granulomatous vasculitis. Antineutrophil cytoplasmic antibodies directed against affinity purified proteinase 3 (p-ANCA) concentrations returned to baseline within 6 months, and the patient has done well during a follow-up period of 2 years. While nodular vasculitis is known to occur in Wegener's granulomatosis, to the best of our knowledge, this case represents the first c-ANCA negative primary pulmonary vasculitis in childhood.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Vasculitis / Nódulo Pulmonar Solitario / Enfermedades Pulmonares Tipo de estudio: Diagnostic_studies Límite: Child / Humans / Male Idioma: En Revista: Pediatr Pulmonol Asunto de la revista: PEDIATRIA Año: 2004 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Estados Unidos
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Vasculitis / Nódulo Pulmonar Solitario / Enfermedades Pulmonares Tipo de estudio: Diagnostic_studies Límite: Child / Humans / Male Idioma: En Revista: Pediatr Pulmonol Asunto de la revista: PEDIATRIA Año: 2004 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Estados Unidos