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A low noise multichannel integrated circuit for recording neuronal signals using microelectrode arrays.
Dabrowski, W; Grybos, P; Litke, A M.
Afiliación
  • Dabrowski W; Faculty of Physics and Nuclear Techniques, University of Mining and Metallurgy, al. Mickiewicza 30 30059 Krakow, Poland. w.dabrowski@ftj.agh.edu.pl
Biosens Bioelectron ; 19(7): 749-61, 2004 Feb 15.
Article en En | MEDLINE | ID: mdl-14709394
This paper reports on the development of a fully integrated 32-channel integrated circuit (IC) for recording neuronal signals in neurophysiological experiments using microelectrode arrays. The IC consists of 32 channels of low-noise preamplifiers and bandpass filters, and an output analog multiplexer. The continuous-time RC active filters have a typical passband of 20-2000 Hz; the low and the high cut-off frequencies can be separately controlled by external reference currents. This chip provides a satisfactory signal-to-noise ratio for neuronal signals with amplitudes greater than 50 microV. For the nominal passband setting, an equivalent input noise of 3 microV rms has been achieved. A single channel occupies 0.35 mm(2) of silicon area and dissipates 1.7 mW of power. The chip was fabricated in a 0.7 microm CMOS process.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Potenciales de Acción / Microelectrodos / Red Nerviosa / Neuronas Tipo de estudio: Diagnostic_studies / Evaluation_studies Límite: Animals Idioma: En Revista: Biosens Bioelectron Asunto de la revista: BIOTECNOLOGIA Año: 2004 Tipo del documento: Article País de afiliación: Polonia Pais de publicación: Reino Unido
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Potenciales de Acción / Microelectrodos / Red Nerviosa / Neuronas Tipo de estudio: Diagnostic_studies / Evaluation_studies Límite: Animals Idioma: En Revista: Biosens Bioelectron Asunto de la revista: BIOTECNOLOGIA Año: 2004 Tipo del documento: Article País de afiliación: Polonia Pais de publicación: Reino Unido