The distribution of 5-HT1D and 5-HT1E binding sites in human brain.
Eur J Pharmacol
; 222(1): 137-42, 1992 Nov 03.
Article
en En
| MEDLINE
| ID: mdl-1468490
Total 5-HT1, 5-HT1D and 5-HT1E binding sites were measured in homogenates of human frontal cortex, hippocampus, amygdala, globus pallidus, caudate and putamen. Combined 5-HT1D/1E sites were the predominant 5-HT1 subtype (66-95% of total 5-HT1 sites in all regions except hippocampus (38% of total 5-HT1 sites). Globus pallidus contained the highest density and the highest proportion of 5HT1D sites (74% of total 5-HT1 sites). 5HT1D sites in the other brain areas accounted for 19-27% of the total 5-HT1 sites. The highest densities and the highest proportions of 5-HT1E sites were in caudate (72%) and putamen (64%) and the lowest density and lowest proportion in hippocampus (16%).
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01-internacional
Base de datos:
MEDLINE
Asunto principal:
Encéfalo
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Química Encefálica
/
Receptores de Serotonina
Límite:
Adult
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Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Eur J Pharmacol
Año:
1992
Tipo del documento:
Article
Pais de publicación:
Países Bajos