NKT cell frequency in Japanese type 1 diabetes.

Oikawa, Yoichi; Shimada, Akira; Yamada, Satoru; Motohashi, Yoshiko; Nakagawa, Yoshinori; Irie, Jun-Ichiro; Maruyama, Taro; Saruta, Takao

Oikawa, Yoichi; Shimada, Akira; Yamada, Satoru; Motohashi, Yoshiko; Nakagawa, Yoshinori; Irie, Jun-Ichiro; Maruyama, Taro; Saruta, Takao.

Afiliación

Oikawa Y; Department of Internal Medicine, Keio University School of Medicine, Tokyo 160-8582, Japan. y-oikawa@mvc.biglobe.ne.jp

Ann N Y Acad Sci ; 1005: 230-2, 2003 Nov.

Article en En | MEDLINE | ID: mdl-14679066

RESUMEN

A numerical and functional deficit of natural killer T (NKT) cells has been reported to be associated with the pathogenesis of Caucasian patients with type 1 diabetes. However, a conflicting finding of a higher frequency of NKT cells (Valpha24+ Vbeta11+ T cells) was observed in islet-associated Ab+ and Ab- Japanese "classic" type 1 diabetes. Here, we combined the data of NKT cell frequency in Ab+ and Ab- "classic" type 1 diabetic patients and then analyzed the relationship between NKT cell frequency and disease activity.

Asunto(s)

Diabetes Mellitus Tipo 1/inmunología; Células Asesinas Naturales/inmunología; Adolescente; Femenino; Hemoglobina Glucada/análisis; Humanos; Japón; Masculino; Persona de Mediana Edad

Buscar en Google

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Células Asesinas Naturales / Diabetes Mellitus Tipo 1 Límite: Adolescent / Female / Humans / Male / Middle aged País/Región como asunto: Asia Idioma: En Revista: Ann N Y Acad Sci Año: 2003 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Estados Unidos

Buscar en Google

Añadir a Mi BVS

Imprimir

XML

PubMed Links