Proton MR spectroscopy in neuroborreliosis: a preliminary study.
Neuroradiology
; 46(1): 26-30, 2004 Jan.
Article
en En
| MEDLINE
| ID: mdl-14663542
We report results of a magnetic resonance spectroscopy (MRS) study in 12 patients with neuroborreliosis. We used a PRESS sequence, placing an 8 cm3 voxel in normal-appearing white matter of the frontal lobe. Peaks indicating N-acetylaspartate (NAA), choline (Cho), creatine (Cr), myo-inositol (mI), lipids (Lip) and lactate (Lac) were identified and ratios of NAA/Cr, Cho/Cr, mI/Cr, Lip/Cr, Lac/Cr calculated. Significant increases in Cho/Cr and Lip/Cr were noted. No abnormality was found in mean NAA/Cr and Lac/Cr, but in four patients there was a decreased NAA peak; mI/Cr ratio was slightly increased. Although the spectroscopic profile in patients with neuroborreliosis seems to be nonspecific, MRS might be useful for assessing tissue damage of the central nervous system.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Encefalopatías
/
Espectroscopía de Resonancia Magnética
/
Neuroborreliosis de Lyme
Tipo de estudio:
Prognostic_studies
Límite:
Adult
/
Aged
/
Female
/
Humans
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Male
/
Middle aged
Idioma:
En
Revista:
Neuroradiology
Año:
2004
Tipo del documento:
Article
País de afiliación:
Polonia
Pais de publicación:
Alemania