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Diagnostic value of sural nerve matrix metalloproteinase-9 in diabetic patients with CIDP.
Jann, S; Bramerio, M A; Beretta, S; Koch, S; Defanti, C A; Toyka, K V; Sommer, C.
Afiliación
  • Jann S; Department of Neurology, Vimercate Hospital, Milan, Italy.
Neurology ; 61(11): 1607-10, 2003 Dec 09.
Article en En | MEDLINE | ID: mdl-14663052
Patients with diabetes mellitus (DM) may develop chronic inflammatory demyelinating polyneuropathy (CIDP), which may be difficult to distinguish from diabetic neuropathy (DNP). Here the authors show that immunoreactivity for matrix metalloproteinase-9 on sural nerve biopsies may help to identify CIDP-DM. In a pilot study on 10 CIDP-DM patients with IV immunoglobulins and tight glycemic control, the CIDP-DM patients had a better outcome than DNP patients treated with tight glycemic control only.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Nervio Sural / Polirradiculoneuropatía Crónica Inflamatoria Desmielinizante / Metaloproteinasa 9 de la Matriz / Complicaciones de la Diabetes Tipo de estudio: Diagnostic_studies / Evaluation_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Neurology Año: 2003 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Estados Unidos
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Nervio Sural / Polirradiculoneuropatía Crónica Inflamatoria Desmielinizante / Metaloproteinasa 9 de la Matriz / Complicaciones de la Diabetes Tipo de estudio: Diagnostic_studies / Evaluation_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Neurology Año: 2003 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Estados Unidos