Improved early detection of cervical intraepithelial lesions by combination of conventional Pap smear and speculoscopy.
Eur J Gynaecol Oncol
; 24(6): 495-9, 2003.
Article
en En
| MEDLINE
| ID: mdl-14658588
PURPOSE: To evaluate the efficacy of the addition of speculoscopy to a Pap smear in cervical cancer screening. METHODS: All women were screened using the Pap smear plus speculoscopy (PapSure) and colposcopy in the multicenter trial. The final diagnosis of each patient was based on a histological evaluation of the colposcopic target biopsy. Results were analyzed using a proportional compare test, sensitivity, specificity and predictive value with significant value determined at less than 0.05. RESULTS: Of 1,717 eligible cases, 26 cases had LGSIL and 16 cases had HGSIL. Of the Pap smears, five cases had LSIL and 14 cases had HGSIL. Of the combination of the PapSure, 23 cases had LGSIL and 16 cases had HGSIL. The sensitivity of the Pap smear to that of PapSure was calculated at 45.2% and 92.9%, respectively (p < 0.001). The estimated cost to detect a cervical lesion using PapSure is less than that of the Pap smear. CONCLUSION: The addition of speculoscopy along with a Pap smear screening results in early detection of cervical lesions in comparison to the Pap smear alone. This screening combination is also more cost-effective and requires fewer visits to the clinic in comparison to a Pap smear screening alone.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Examen Físico
/
Frotis Vaginal
/
Displasia del Cuello del Útero
/
Neoplasias del Cuello Uterino
/
Prueba de Papanicolaou
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
/
Evaluation_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
/
Screening_studies
Límite:
Adult
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Aged
/
Aged80
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Female
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Humans
/
Middle aged
País/Región como asunto:
Asia
Idioma:
En
Revista:
Eur J Gynaecol Oncol
Año:
2003
Tipo del documento:
Article
Pais de publicación:
Singapur