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Applications of ovarian tissue transplantation in experimental biology and medicine.
Torrents, E; Boiso, I; Barri, P N; Veiga, A.
Afiliación
  • Torrents E; Servicio de Medicina de la Reproducción, Departamento de Obstetricia y Ginecología, Institut Universitari Dexeus, Paseo Bonanova 89-91, 08017 Barcelona, Spain.
Hum Reprod Update ; 9(5): 471-81, 2003.
Article en En | MEDLINE | ID: mdl-14640379
Nowadays, high-dose chemotherapy and radiotherapy treatments for cancer are more effective but can severely affect the ovarian follicular store, compromising the fertility of surviving young patients. A promising alternative to prevent fertility loss in these patients is the cryopreservation and transplantation of ovarian tissue. Slices of animal and human ovarian tissue have been shown to survive the cryopreservation process. After transplantation, follicular development and restoration of hormone secretion have been observed in animal and human studies. This review addresses recent developments on ovarian tissue transplantation in animals and humans. We also illustrate the indications and technical difficulties of the procedure and the ethical issues that should be considered.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ovario / Trasplante de Tejidos Aspecto: Ethics Límite: Animals / Female / Humans Idioma: En Revista: Hum Reprod Update Asunto de la revista: EMBRIOLOGIA / MEDICINA REPRODUTIVA Año: 2003 Tipo del documento: Article País de afiliación: España Pais de publicación: Reino Unido
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ovario / Trasplante de Tejidos Aspecto: Ethics Límite: Animals / Female / Humans Idioma: En Revista: Hum Reprod Update Asunto de la revista: EMBRIOLOGIA / MEDICINA REPRODUTIVA Año: 2003 Tipo del documento: Article País de afiliación: España Pais de publicación: Reino Unido