Sarcoid-related uveitis occurring during etanercept therapy.

Hashkes, P J; Shajrawi, I

Hashkes, P J; Shajrawi, I.

Afiliación

Hashkes PJ; Pediatric Rheumatology Section, Department of Rheumatic Diseases, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, Ohio 44195, USA. hashkep@ccf.org

Clin Exp Rheumatol ; 21(5): 645-6, 2003.

Article en En | MEDLINE | ID: mdl-14611117

RESUMEN

We report the case of a 7-year-old boy who was initially diagnosed as having polyarticular juvenile idiopathic arthritis. Clinical and laboratory features of overt sarcoidosis became evident early during etanercept therapy when he developed acute panuveitis, papular skin rash and elevated levels of angiotensin-converting enzyme. Non-caseating granulomas were present in the liver. Uveitis resolved upon discontinuation of etanercept and systemic administration of corticosteroids. In rare cases expression of autoimmune disorders or expanded clinical features of these disorders may occur during etanercept treatment.

Asunto(s)

Antiinflamatorios no Esteroideos/efectos adversos; Enfermedades Autoinmunes/inducido químicamente; Inmunoglobulina G/efectos adversos; Sarcoidosis/inducido químicamente; Uveítis/inducido químicamente; Artritis Juvenil/diagnóstico; Niño; Diagnóstico Diferencial; Etanercept; Humanos; Masculino; Receptores del Factor de Necrosis Tumoral; Sarcoidosis/diagnóstico

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sarcoidosis / Enfermedades Autoinmunes / Uveítis / Inmunoglobulina G / Antiinflamatorios no Esteroideos Tipo de estudio: Diagnostic_studies Límite: Child / Humans / Male Idioma: En Revista: Clin Exp Rheumatol Año: 2003 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Italia

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