Cell adhesion in the stromal regulation of haemopoiesis.
Baillieres Clin Haematol
; 5(3): 619-52, 1992 Jul.
Article
en En
| MEDLINE
| ID: mdl-1457965
Haemopoiesis occurs in close physical contact with elements of the bone marrow stroma. This review examines some adhesion molecules which are expressed in haemopoietic environments. These molecules may act to maintain cell contact between haemopoietic progenitors and the cellular and extracellular matrix elements of the marrow stroma. A review is undertaken of several families of adhesion molecules and their ligands, including integrins, CD44, LEC-CAMs, CAMs and variant glycosylation patterns expressed by haemopoietic cells. Both CD44 and integrin receptors have been implicated in mediating important cellular interactions within the haemopoietic system and the significance of these and other molecules in haemopoiesis is discussed.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Hematopoyesis
Tipo de estudio:
Prognostic_studies
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Baillieres Clin Haematol
Asunto de la revista:
HEMATOLOGIA
Año:
1992
Tipo del documento:
Article
Pais de publicación:
Reino Unido