[High frequency ventilation in the newborn. Study of 27 cases]. / Ventilación de alta frecuencia en el recién nacido. Estudio de 27 casos.
An Esp Pediatr
; 37(5): 361-5, 1992 Nov.
Article
en Es
| MEDLINE
| ID: mdl-1456616
ABSTRACT
PIP: Clinical records of 27 newborns treated with high frequency ventilation in a hospital neonatal service in Madrid were retrospectively studied. High frequency ventilation is a technique with specific indications that has recently been applied in some neonatal pathologies as an alternative to conventional ventilation. The respirators, model 2 Volumetric Diffusive Respirators, were used in 24 of the 27 cases because of failure of conventional ventilation. The 27 newborns weighed an average of 1850 +or- 944 g and ranged from 900 to 4000 g. Their average gestational age was 32 +or- 4 weeks, and the range was 26-42 weeks. 19 had respiratory difficulties stemming from hyaline membrane disease, 3 had congenital diaphragmatic hernias, 2 had pulmonary hypertension, and one each had meconium aspiration syndrome, septic shock from group B streptococcus, and diaphragmatic agenesia. 66% were delivered by cesarean. The pH, paCO2, and paO2 improved significantly between 2 and 6 hours after initiation of HFV treatment. Values in the normal range were reached at 6.5 +or- 14 hours for pH, 30 +or- 50 hours for paCO2, and 6.5 +or- 10 hours for paO2. No hemodynamic modifications were attributed to HFV. The most significant complications were ectopic air (62%) and necrotizing tracheobronchitis (25%). Broncopulmonary dysphasia was diagnosed in 20%, ductus in 33%, and intracraneal hemorrhage in 25%. The case fatality rate was 70%. Ten newborns improved definitively with HFV and proceeded to conventional ventilation. Two later succumbed to other causes. The study showed that HFV can lead to serious complications and should be applied with great prudence despite it great potential benefit.
Palabras clave
Age Factors; Biology; Case Studies; Clinical Research; Demographic Factors; Developed Countries; Diseases; Europe; Infant; Mediterranean Countries; Neonatal Diseases And Abnormalities; Physiology; Population; Population Characteristics; Pulmonary Effects; Research Methodology; Respiratory Insufficiency; Retrospective Studies; Southern Europe; Spain; Studies; Treatment; Youth
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Síndrome de Dificultad Respiratoria del Recién Nacido
/
Ventilación de Alta Frecuencia
/
Hernias Diafragmáticas Congénitas
/
Enfermedad de la Membrana Hialina
Tipo de estudio:
Prognostic_studies
Límite:
Humans
/
Newborn
País/Región como asunto:
Europa
Idioma:
Es
Revista:
An Esp Pediatr
Año:
1992
Tipo del documento:
Article
Pais de publicación:
España