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Effect of monensin on Mayaro virus replication in monkey kidney and Aedes albopictus cells.
De Campos, R M; Ferreira, D F; Da Veiga, V F; Rebello, M A; Rebello, M C S.
Afiliación
  • De Campos RM; Department of Virology, Prof. Paulo de Góes Institute of Microbiology, Federal University of Rio de Janeiro, Rio de Janeiro, CEP 21941-590, RJ, Brazil.
Acta Virol ; 47(2): 113-9, 2003.
Article en En | MEDLINE | ID: mdl-14524478
The effect of a cationic ionophore, monensin, on the replication of Mayaro virus in monkey kidney TC7 and Aedes albopictus cells has been studied. Treatment of these cells with 1 micromol/l monensin during infection did not affect the virus protein synthesis but inhibited severely the virus replication. Electron microscopy of the cells infected with Mayaro virus and treated with monensin revealed that the morphogenesis of Mayaro virus was impaired in TC7 but not in A. albopictus cells.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Virales / Replicación Viral / Monensina / Alphavirus Límite: Animals Idioma: En Revista: Acta Virol Año: 2003 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Eslovaquia
Buscar en Google
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PubMed Links

Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Virales / Replicación Viral / Monensina / Alphavirus Límite: Animals Idioma: En Revista: Acta Virol Año: 2003 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Eslovaquia