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A combined solid-state and submerged cultivation integrated with adsorptive product extraction for production of Monascus red pigments.
Hsu, F-L; Wang, P-M; Lu, S-Y; Wu, W-T.
Afiliación
  • Hsu FL; Department of Chemical Engineering, National Tsing-Hua University, Hsin-Chu, Taiwan 30043, Republic of China.
Bioprocess Biosyst Eng ; 25(3): 165-8, 2002 Sep.
Article en En | MEDLINE | ID: mdl-14508674
A process taking advantages of combined solid-state and submerged cultivation of Monascus for red pigment production and integration of a product removal unit was developed. The solid-state cultivation was carried out in a 5 l fermentor, with rice being used not only as the substrate but also the support for Monascus. The inclusion of rice submergence and integration of product separation were achieved by intermittently rinsing the rice with monosodium glutamate (MSG) solutions every 12 h followed by an adsorptive extraction of the red pigment dissolved in the rinsing solution. With this new process, the Monascus red pigment production was increased by 24% as compared with that by the plain fixed-bed cultivation.
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Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Bioprocess Biosyst Eng Asunto de la revista: BIOTECNOLOGIA / ENGENHARIA BIOMEDICA Año: 2002 Tipo del documento: Article País de afiliación: China Pais de publicación: Alemania
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Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Bioprocess Biosyst Eng Asunto de la revista: BIOTECNOLOGIA / ENGENHARIA BIOMEDICA Año: 2002 Tipo del documento: Article País de afiliación: China Pais de publicación: Alemania