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Antibody responses elicited against the Treponema pallidum repeat proteins differ during infection with different isolates of Treponema pallidum subsp. pallidum.
Leader, Brandon T; Hevner, Karin; Molini, Barbara J; Barrett, Lynn K; Van Voorhis, Wesley C; Lukehart, Sheila A.
Afiliación
  • Leader BT; Department of Pathobiology, University of Washington, Seattle, WA 98195-7185, USA.
Infect Immun ; 71(10): 6054-7, 2003 Oct.
Article en En | MEDLINE | ID: mdl-14500529
Variation in the expression of the different Tpr proteins in the syphilis spirochete, Treponema pallidum subsp. pallidum, may have important implications in its ability to evade host immune detection and cause persistent infection. In the present study we examined the pattern of antibody responsiveness to different Tpr members during infection with three isolates of T. pallidum. There was variability in the specificities and temporal patterns of reactivity of the antibodies elicited against the individual Tpr proteins, suggesting that isolates may express different repertoires of Tpr proteins during infection.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas de la Membrana Bacteriana Externa / Treponema pallidum / Anticuerpos Antibacterianos Límite: Animals / Humans Idioma: En Revista: Infect Immun Año: 2003 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas de la Membrana Bacteriana Externa / Treponema pallidum / Anticuerpos Antibacterianos Límite: Animals / Humans Idioma: En Revista: Infect Immun Año: 2003 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos