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Gastrointestinal pneumocystosis in HIV-infected patients on aerosolized pentamidine: report of five cases and literature review.
Dieterich, D T; Lew, E A; Bacon, D J; Pearlman, K I; Scholes, J V.
Afiliación
  • Dieterich DT; New York University Medical Center, New York.
Am J Gastroenterol ; 87(12): 1763-70, 1992 Dec.
Article en En | MEDLINE | ID: mdl-1449138
Extrapulmonary infection with Pneumocystis carinii in AIDS patients on aerosolized pentamidine is occurring more frequently. We report five patients diagnosed with gastrointestinal pneumocystosis while on aerosolized pentamidine prophylaxis and have identified infections involving the peritoneum, liver, and transverse colon, as well as stomach and duodenum. Physicians should have a high index of suspicion for extrapulmonary pneumocystosis, especially involving the gastrointestinal system, in HIV-infected patients, and early diagnosis must be pursued aggressively. The use of aerosolized pentamidine as prophylaxis for P. carinii pneumonia is not protective against gastrointestinal pneumocystosis because of inadequate systemic distribution of the drug. To our knowledge, this is the first report in a clinical journal documenting and photographing P. carinii organisms in ascitic fluid.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pentamidina / Infecciones por VIH / Infecciones por Pneumocystis / Enfermedades Gastrointestinales Tipo de estudio: Prognostic_studies / Screening_studies Límite: Adult / Humans / Male / Middle aged Idioma: En Revista: Am J Gastroenterol Año: 1992 Tipo del documento: Article Pais de publicación: Estados Unidos
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pentamidina / Infecciones por VIH / Infecciones por Pneumocystis / Enfermedades Gastrointestinales Tipo de estudio: Prognostic_studies / Screening_studies Límite: Adult / Humans / Male / Middle aged Idioma: En Revista: Am J Gastroenterol Año: 1992 Tipo del documento: Article Pais de publicación: Estados Unidos