Cognition in homozygous beta-thalassemia disease: a multichannel auditory event-related potential (P300) study.
Electromyogr Clin Neurophysiol
; 32(10-11): 531-5, 1992.
Article
en En
| MEDLINE
| ID: mdl-1446585
Auditory Event-Related Potentials (AERP) were elicited in 25 beta-thalassemic patients, three days before and three days after a blood transfusion. The amplitude, latency and topographic distribution of P300 (P3) as well as N1, P2, N2 components were measured for the two assessment times. No significant differences in either amplitude, latency or topography were observed between the two situations, but thalassemic patients had significantly prolonged P3 latencies comparing to controls though none of them exceeded 3 standard deviations of the control mean values. Regarding P3 topography, 10 out of 25 patients showed a right centroparietal distribution area. It is concluded that information processing, as far as it is reflected in AERP components is impaired in thalassemic patients and blood transfusion have no significant influence in cognitive functions.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Encéfalo
/
Talasemia beta
/
Cognición
/
Potenciales Evocados Auditivos
Límite:
Adolescent
/
Adult
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Female
/
Humans
/
Male
Idioma:
En
Revista:
Electromyogr Clin Neurophysiol
Año:
1992
Tipo del documento:
Article
País de afiliación:
Grecia
Pais de publicación:
Bélgica