Sex-linked, androgen-dependent differences in renal retention of trimethylselenonium ions.
Biol Trace Elem Res
; 34(3): 257-63, 1992 Sep.
Article
en En
| MEDLINE
| ID: mdl-1384616
The metabolism of trimethylselenonium ions (TMSe) was studied in male and female rats during maturation. Selenium (Se) retention in the whole body as well as in organs was found to be significantly higher in male rats than in female a few hours after parenteral administration of TMSe. The pronounced Se accumulation was observed in male kidneys. This sex-linked difference was dependent on the presence of gonads and started to be manifested with sexual maturation during the third decade of postnatal life. The effects of steroid hormones on the retention of Se from TMSe were examined in female and castrated male rats. The results indicate that TMSe metabolism in rat kidneys may be influenced by androgen steroids.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Selenio
/
Testosterona
/
Caracteres Sexuales
/
Compuestos de Selenio
/
Riñón
Límite:
Animals
Idioma:
En
Revista:
Biol Trace Elem Res
Año:
1992
Tipo del documento:
Article
Pais de publicación:
Estados Unidos