Antitussive activity of Abies webbiana Lindl. leaf extract against sulphur dioxide-induced cough reflex in mice.

Nayak, S S; Ghosh, A K; Srikanth, K; Debnath, B; Jha, T

Nayak, S S; Ghosh, A K; Srikanth, K; Debnath, B; Jha, T.

Afiliación

Nayak SS; Natural Science Laboratory, Department of Pharmaceutical Technology, Jadavpur University Kolkata--700 032, India.

Phytother Res ; 17(8): 930-2, 2003 Sep.

Article en En | MEDLINE | ID: mdl-13680827

RESUMEN

The methanol extract of A. webbiana Lindl was evaluated for its effect on a cough model induced by sulphur dioxide gas in mice. When administered orally it exhibited significant antitussive activity compared with the control in a dose dependent manner. The antitussive activity of the extract was compared with that of codeine phosphate, a prototype antitussive agent. The A. webbiana leaf extract (400 and 600 mg/kg) showed maximum inhibition of cough frequency by 71.69% and 78.67%, respectively, when compared with the control group and was comparable in effect to codeine phosphate.

Asunto(s)

Abies; Antitusígenos/farmacología; Tos/prevención & control; Fitoterapia; Extractos Vegetales/farmacología; Administración Oral; Animales; Antitusígenos/administración & dosificación; Antitusígenos/uso terapéutico; Tos/inducido químicamente; Relación Dosis-Respuesta a Droga; Femenino; Masculino; Ratones; Extractos Vegetales/administración & dosificación; Extractos Vegetales/uso terapéutico; Hojas de la Planta; Dióxido de Azufre

Buscar en Google

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Antitusígenos / Extractos Vegetales / Tos / Abies / Fitoterapia Límite: Animals Idioma: En Revista: Phytother Res Asunto de la revista: TERAPIAS COMPLEMENTARES Año: 2003 Tipo del documento: Article País de afiliación: India Pais de publicación: Reino Unido

Buscar en Google

Añadir a Mi BVS

Imprimir

XML

PubMed Links