Studies on p40, the leucine zipper motif-containing protein encoded by the first open reading frame of an active human LINE-1 transposable element.
J Biol Chem
; 267(28): 19765-8, 1992 Oct 05.
Article
en En
| MEDLINE
| ID: mdl-1328181
Full-length human LINE-1 retrotransposons encode p40 proteins with varying electrophoretic mobilities under denaturing conditions. The p40 expressed from the first open reading frame in the LINE-1 copy designated L1.2A co-electrophoreses with the endogenous p40 in human teratocarcinoma cells. This finding is consistent with previous data indicating that L1.2A is an active element. The amino acid sequence in the central region of the L1.2A p40 accounts, at least in part, for its characteristic mobility. This region includes sequences which can, in principle, form a leucine zipper.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Péptidos
/
Elementos Transponibles de ADN
/
Proteínas
/
Leucina Zippers
/
Proteínas de Unión al ADN
Límite:
Humans
Idioma:
En
Revista:
J Biol Chem
Año:
1992
Tipo del documento:
Article
Pais de publicación:
Estados Unidos