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[Diazepam versus midazolam as pre-endoscopic medication]. / Diazepam versus midazolam como medicación pre-endoscópica.
Córdova Villalobos, J A; Rojas Hernández, R; Hernández Ortiz, T M; Ramírez Barba, E J.
Afiliación
  • Córdova Villalobos JA; Universidad de Guanajuato, Facultad de Medicina de León. IMSS. Hospital de Especialidades.
Rev Gastroenterol Mex ; 57(4): 238-41, 1992.
Article en Es | MEDLINE | ID: mdl-1308305
A prospective randomized double blind study was carried out on 60 patients undergoing elective gastrointestinal endoscopy. Patients in group A were sedated with diazepam (0.15 mg/kg) and those in group B received midazolam (0.10 mg/kg). There were no differences between the groups in age, sex, previous drug intake, level of anxiety prior to the procedure and from the endoscopist point of view the easiness to perform the studies. The group of patients who received midazolam (B) showed a significantly greater sedation, had less pain in the site of injection, their retrograde amnesia was more effective and tolerated much better the overall procedure (p < 0.05). There were no complications in either group. The cost per dosage was 2:1 greater with midazolam. It is concluded that midazolam has some advantages over diazepam used for sedation of patients undergoing gastrointestinal endoscopy. The time for recovery and cost are its disadvantages.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Premedicación / Midazolam / Sedación Consciente / Endoscopía Gastrointestinal / Diazepam Tipo de estudio: Clinical_trials / Observational_studies / Prevalence_studies / Risk_factors_studies Límite: Adolescent / Adult / Female / Humans / Male / Middle aged Idioma: Es Revista: Rev Gastroenterol Mex Año: 1992 Tipo del documento: Article Pais de publicación: México
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Premedicación / Midazolam / Sedación Consciente / Endoscopía Gastrointestinal / Diazepam Tipo de estudio: Clinical_trials / Observational_studies / Prevalence_studies / Risk_factors_studies Límite: Adolescent / Adult / Female / Humans / Male / Middle aged Idioma: Es Revista: Rev Gastroenterol Mex Año: 1992 Tipo del documento: Article Pais de publicación: México