Successful treatment of muscle sarcoidosis with thalidomide.

Walter, M C; Lochmüller, H; Schlotter-Weigel, B; Meindl, T; Müller-Felber, W

Walter, M C; Lochmüller, H; Schlotter-Weigel, B; Meindl, T; Müller-Felber, W.

Afiliación

Walter MC; Friedrich-Baur-Institute, Department of Neurology, Ludwig-Maximilians University of Munich, Ziemssenstr. 1a, 80336 Munich, Germany. Maggie.Walter@lrz.uni-muenchen.de

Acta Myol ; 22(1): 22-5, 2003 May.

Article en En | MEDLINE | ID: mdl-12966701

RESUMEN

A 36-year-old male patient suffered from therapy resistant sarcoidosis with long-standing contractures, myopathy, skin lesions and pulmonary changes. Low-dose therapy with thalidomide (50 mg/day) was well tolerated, and the patient rapidly improved. Thalidomide was effective for muscular, cutaneous, and pulmonary involvement in our patient. This is the first report on the efficacy of thalidomide in muscle sarcoidosis. Therefore, thalidomide may become a second-line agent in patients with severe muscle and skin involvement, but further studies are warranted.

Asunto(s)

Inmunosupresores/uso terapéutico; Enfermedades Musculares/tratamiento farmacológico; Sarcoidosis/tratamiento farmacológico; Talidomida/uso terapéutico; Adulto; Humanos; Imagen por Resonancia Magnética; Masculino; Enfermedades Musculares/patología; Sarcoidosis/patología

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sarcoidosis / Talidomida / Inmunosupresores / Enfermedades Musculares Límite: Adult / Humans / Male Idioma: En Revista: Acta Myol Asunto de la revista: CARDIOLOGIA / FISIOLOGIA Año: 2003 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Italia

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