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Outcomes of patients treated with fluticasone propionate or montelukast sodium.
Allen-Ramey, Felicia C; Duong, Phong T; Goodman, David C; Sajjan, Shiva G; Nelsen, Linda M; Markson, Leona.
Afiliación
  • Allen-Ramey FC; Department of Epidemiology, Merck and Company, West Point, Pennsylvania, USA. felicia_ramey@merck.com
Manag Care Interface ; 16(8): 30-5, 2003 Aug.
Article en En | MEDLINE | ID: mdl-12964550
The authors conducted a retrospective database study of patients with asthma (age range, 6-55 yr) who initiated fluticasone propionate or montelukast sodium treatment between an index period of July 1998 and June 1999. All patients were observed for 12 months before and after the index period. Changes in asthma-related hospitalizations, emergency department visits, oral corticosteroid use, and short-acting beta-agonist use were analyzed. The odds of postindex asthma-related events were estimated. In multivariate analysis, use of a short-acting beta agonist (SABA) was significantly associated with fluticasone treatment (odds ratio [OR], 1.65; 95% confidence interval [CI], 1.21-2.26) and preindex use of SABAs (OR, 1.84; 95% CI, 1.34-2.53). In this managed care population, fluticasone and montelukast provided similar effectiveness.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Quinolinas / Asma / Evaluación de Resultado en la Atención de Salud / Antiasmáticos / Androstadienos / Acetatos Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Adolescent / Adult / Child / Female / Humans / Male / Middle aged País/Región como asunto: America do norte Idioma: En Revista: Manag Care Interface Asunto de la revista: SERVICOS DE SAUDE Año: 2003 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Quinolinas / Asma / Evaluación de Resultado en la Atención de Salud / Antiasmáticos / Androstadienos / Acetatos Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Adolescent / Adult / Child / Female / Humans / Male / Middle aged País/Región como asunto: America do norte Idioma: En Revista: Manag Care Interface Asunto de la revista: SERVICOS DE SAUDE Año: 2003 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos