2-(2-Naphthyloxy)acetate derivatives. II. A new class of antiamnesic agents.
Acta Crystallogr C
; 59(Pt 8): o467-9, 2003 Aug.
Article
en En
| MEDLINE
| ID: mdl-12909779
The title compounds, 4-(2-naphthyloxymethylcarbonyl)morpholine, C(16)H(17)NO(3), (I), and 4-methyl-1-(2-naphthyloxymethylcarbonyl)piperazine, C(17)H(20)N(2)O(2), (II), are potential antiamnesics. The morpholine ring in (I) and the piperazine ring in (II) adopt chair conformations. In (I), the molecules are linked by weak intermolecular C-H.O interactions into chains that have a graph-set motif of C(10), while in (II), the molecules are linked by weak intermolecular C-H.O interactions that generate two C(7) graph-set motifs. The dihedral angle between the naphthalene moiety and the best plane through the morpholine ring is 20.62 (4) degrees in (I), while the naphthalene moiety is oriented nearly perpendicular to the mean plane of the piperazine ring in (II).
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Amnesia
/
Acetatos
/
Naftalenos
Idioma:
En
Revista:
Acta Crystallogr C
Año:
2003
Tipo del documento:
Article
País de afiliación:
India
Pais de publicación:
Estados Unidos