Histological behaviour of chronic hepatitis in patients treated with alpha interferon.

Villari, D; Raimondo, G; Freni, M A; Rodinò, G; Aiello, A; Fava, A; Longo, G; Batolo, D

Villari, D; Raimondo, G; Freni, M A; Rodinò, G; Aiello, A; Fava, A; Longo, G; Batolo, D.

Afiliación

Villari D; Dipartimento di Patologia Umana, Università di Messina, Italy.

Pathology ; 24(4): 243-6, 1992 Oct.

Article en En | MEDLINE | ID: mdl-1289764

RESUMEN

To evaluate the histological effects of alpha Interferon (IFN) therapy, serial liver biopsy specimens from 30 patients with chronic hepatitis were studied. The biopsies were examined using a scoring system. After 12 mths of IFN therapy responders were 8 out of 11 HBV infected patients, 10 out of 12 HCV infected patients and only 1 out of 7 patients with cryptogenetic hepatitis. As spontaneous improvement of hepatic changes is infrequent, our data indicate that in terms of histological patterns interferon therapy is effective in chronic viral hepatitis.

Asunto(s)

Hepatitis B/patología; Hepatitis C/patología; Hepatitis Crónica/patología; Interferón-alfa/uso terapéutico; Hepatitis B/terapia; Hepatitis C/terapia; Hepatitis Crónica/terapia; Humanos

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Interferón-alfa / Hepatitis C / Hepatitis B / Hepatitis Crónica Límite: Humans Idioma: En Revista: Pathology Año: 1992 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Reino Unido

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