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Compliance with antihypertensive therapy after renal artery stenting.
Reddy, Bhagat K; Kennedy, David J; Colyer, William R; Burket, Mark W; Thomas, William J; Khuder, Sadik A; Shapiro, Joseph I; Topp, Robert V; Cooper, Christopher J.
Afiliación
  • Reddy BK; Department of Medicine, Medical College of Ohio, Toledo, OH 43614-2598, USA.
Biol Res Nurs ; 5(1): 37-46, 2003 Jul.
Article en En | MEDLINE | ID: mdl-12886669
Hypertension is an important clinical endpoint after renal artery revascularization for renal artery stenosis (RAS). Medication compliance is a critical determinant of blood pressure control. Although factors influencing compliance are known in essential hypertension, they have not been evaluated in studies investigating renal artery revascularization. The aim of this study was to assess the determinants of compliance to antihypertensive therapy in patients with RAS following renal artery stent placement (RASP). A cross-sectional study evaluating blood pressure, antihypertensive medications, quality of life, compliance, and determinants of compliance to antihypertensive therapy was undertaken in 112 patients undergoing RASP. Additionally, cardiovascular risk factors, antihypertensive medications, and cardiovascular history were reported. Self-reported compliance was 79% +/- 24% (scale of 0% [none] to 100% [complete] compliance) in patients after RASP. Determinants of compliance by multivariate analysis included physical symptoms, which correlated negatively to compliance and included loss of appetite (r2 = 0.26, P < 0.0001), dizziness (r2 = 0.06, P < 0.01), and cough (r2 = 0.03, P < 0.05). Systolic blood pressure correlated positively with compliance (r2 = 0.03, P < 0.05). The number or class of antihypertensive medications did not influence compliance. Patients' physical symptoms and level of systolic blood pressure, rather than the number or class of medications, influence compliance in patients with continued hypertension after RASP. Attention to physical symptoms may help to improve blood pressure control in this population.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Obstrucción de la Arteria Renal / Stents / Cooperación del Paciente / Hipertensión Renovascular / Antihipertensivos Tipo de estudio: Diagnostic_studies / Etiology_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Qualitative_research / Risk_factors_studies Aspecto: Patient_preference Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Biol Res Nurs Asunto de la revista: ENFERMAGEM / MEDICINA Año: 2003 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Obstrucción de la Arteria Renal / Stents / Cooperación del Paciente / Hipertensión Renovascular / Antihipertensivos Tipo de estudio: Diagnostic_studies / Etiology_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Qualitative_research / Risk_factors_studies Aspecto: Patient_preference Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Biol Res Nurs Asunto de la revista: ENFERMAGEM / MEDICINA Año: 2003 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos