[Inverse association between smoking and idiopathic Parkinson's disease]. / Asociación inversa entre consumo de tabaco y enfermedad de Parkinson idiopática.
An Sist Sanit Navar
; 22(1): 17-23, 1999.
Article
en Es
| MEDLINE
| ID: mdl-12886357
An evaluation is made of the effect of smoking during the period of life between 20 and 50 years of age and idiopathic Parkinson's disease in a case-control study carried out in Navarra. An inverse association is observed: for the number of smokers (OR = 0.66, CI 90% 0.41-1.05); for the number of years smoking (OR =0.22, CI 90% 0.05-0.97); and for the quantity of cigarettes smoked (z = 2.2298, p = 0.02). Likewise, a dose-response relationship exists between the number of cigarettes consumed and the risk of Parkinson's disease (p = 0.01). The same effect is maintained on analysing the data by matching 1:1 (OR = 0.59, CI 90% 0.31-1.10). All of this contributes to giving consistency to the protective effect of smoking against idiopathic Parkinson's disease. The anti-oxidant status, measured by means of different parameters in peripheral blood, is lower in the cases than in the tests for reduced glutathione (GSH) (p = 0.001) and is an independent variable with respect to smoking.
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Colección:
01-internacional
Base de datos:
MEDLINE
Tipo de estudio:
Observational_studies
/
Risk_factors_studies
Idioma:
Es
Revista:
An Sist Sanit Navar
Asunto de la revista:
SAUDE PUBLICA
Año:
1999
Tipo del documento:
Article
Pais de publicación:
España