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The Hopkins Lupus Pregnancy Center: 1987-1991 update.
Petri, M; Howard, D; Repke, J; Goldman, D W.
Afiliación
  • Petri M; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Am J Reprod Immunol ; 28(3-4): 188-91, 1992.
Article en En | MEDLINE | ID: mdl-1283682
The course of pregnancy in patients with systemic lupus erythematosus is not known. The Hopkins Lupus Pregnancy Center has followed 64 patients (74 pregnancies) prospectively since 1987. Patients are seen monthly and clinical and pregnancy-related data collected, with particular emphasis on the occurrence of lupus flare. Flare rate during pregnancy was 1.63 per person-year, compared to 0.64-0.65 after delivery or in non-pregnant patients. Flare did not influence pregnancy outcome. Low serum C3 or C4 and high anticardiolipin antibody predicted pregnancy loss, and prednisone dose, aspirin use, diastolic second trimester blood pressure, C3 at first visit, and race predicted preterm birth. Maternal flare and preterm birth are important risks in lupus pregnancy. The latter can be predicted from maternal pregnancy data.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Complicaciones del Embarazo / Resultado del Embarazo / Lupus Eritematoso Sistémico Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Female / Humans / Newborn / Pregnancy País/Región como asunto: America do norte Idioma: En Revista: Am J Reprod Immunol Año: 1992 Tipo del documento: Article Pais de publicación: Dinamarca
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Complicaciones del Embarazo / Resultado del Embarazo / Lupus Eritematoso Sistémico Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Female / Humans / Newborn / Pregnancy País/Región como asunto: America do norte Idioma: En Revista: Am J Reprod Immunol Año: 1992 Tipo del documento: Article Pais de publicación: Dinamarca