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Antibiotic resistance and serotype distribution of Streptococcus pneumoniae colonizing rural Malawian children.
Feikin, Daniel R; Davis, Mollie; Nwanyanwu, Okey C; Kazembe, Peter N; Barat, Lawrence M; Wasas, Avril; Bloland, Peter B; Ziba, Charles; Capper, Thora; Huebner, Robin E; Schwartz, Ben; Klugman, Keith P; Dowell, Scott F.
Afiliación
  • Feikin DR; Respiratory Diseases Branch, Division of Bacterial and Mycotic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, PHS/DHHS, 1600 Clifton Road, Mailstop C23, Atlanta, GA 30333, USA. drf0@cdc.gov
Pediatr Infect Dis J ; 22(6): 564-7, 2003 Jun.
Article en En | MEDLINE | ID: mdl-12828156
Nasopharyngeal swabs were taken from 906 Malawian children <5 years old visiting rural health clinics. Pneumococcal colonization was high, 84% among all children, and occurred early, 65% of it in children <3 months old. Among pneumococcal isolates 46% were nonsusceptible to trimethoprim-sulfamethoxazole, and 21% were nonsusceptible to penicillin. Trimethoprim-sulfamethoxazole use in the previous month was a risk factor for trimethoprim-sulfamethoxazole and penicillin nonsusceptibility. Forty-three percent of isolates were serotypes included in the 7-valent pneumococcal conjugate vaccine, and 37% were vaccine-related serotypes, particularly 6A and 19A.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Penicilinas / Streptococcus pneumoniae / Combinación Trimetoprim y Sulfametoxazol / Resistencia a Múltiples Medicamentos Tipo de estudio: Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Límite: Child, preschool / Female / Humans / Infant / Male País/Región como asunto: Africa Idioma: En Revista: Pediatr Infect Dis J Asunto de la revista: DOENCAS TRANSMISSIVEIS / PEDIATRIA Año: 2003 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Penicilinas / Streptococcus pneumoniae / Combinación Trimetoprim y Sulfametoxazol / Resistencia a Múltiples Medicamentos Tipo de estudio: Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Límite: Child, preschool / Female / Humans / Infant / Male País/Región como asunto: Africa Idioma: En Revista: Pediatr Infect Dis J Asunto de la revista: DOENCAS TRANSMISSIVEIS / PEDIATRIA Año: 2003 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos