Regional differences in the distribution of capsaicin-sensitive target-identified adult rat dorsal root ganglion neurons.

Hu-Tsai, M; Winter, J; Woolf, C J

Hu-Tsai, M; Winter, J; Woolf, C J.

Afiliación

Hu-Tsai M; Department of Anatomy and Developmental Biology, University College London, UK.

Neurosci Lett ; 143(1-2): 251-4, 1992 Aug 31.

Article en En | MEDLINE | ID: mdl-1279477

RESUMEN

A retrograde labelling technique combined with a cobalt uptake assay in cultured adult rat dorsal root ganglion (DRG) neurons were applied to study the distribution of capsaicin sensitivity in relation to different peripheral targets. This study shows that there are regional differences between skin, skeletal muscle and urinary bladder; 20-30% of skin afferents, 40% of muscle afferents and 60% of bladder afferents were found to be capsaicin-senditive. This may reflect differences in the proportion of chemosensitive afferents innervating different peripheral tissues.

Asunto(s)

Capsaicina/farmacología; Ganglios Espinales/citología; Neuronas Aferentes/efectos de los fármacos; Animales; Cobalto/metabolismo; Miembro Posterior/inervación; Canales Iónicos/efectos de los fármacos; Canales Iónicos/metabolismo; Fibras Nerviosas/efectos de los fármacos; Neuronas Aferentes/metabolismo; Ratas; Ratas Sprague-Dawley; Vejiga Urinaria/inervación

Buscar en Google

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Capsaicina / Ganglios Espinales / Neuronas Aferentes Tipo de estudio: Diagnostic_studies Límite: Animals Idioma: En Revista: Neurosci Lett Año: 1992 Tipo del documento: Article Pais de publicación: Irlanda

Buscar en Google

Añadir a Mi BVS

Imprimir

XML

PubMed Links