Moricizine induced increase in pacing threshold.

Girod, John P; Marrouche, Nassir; Chen, Michael S; Natale, Andrea

Girod, John P; Marrouche, Nassir; Chen, Michael S; Natale, Andrea.

Afiliación

Girod JP; Department of Cardiovascular Medicine, Cleveland Clinic Foundation, 9500 Euclid Ave., Desk F-15, Cleveland, OH 44195, USA.

Pacing Clin Electrophysiol ; 26(1 Pt 1): 110-1, 2003 Jan.

Article en En | MEDLINE | ID: mdl-12685150

RESUMEN

A 72-year-old woman who was experiencing incessant ventricular tachycardia and recurrent automatic implantable cardioverter defibrillator (AICD) firing despite amiodarone therapy was referred to the Cleveland Clinic Foundation. Myocardial ischemia and infarction were ruled out by standard means. Several antiarrhythmic medications were tried previously without success. Moricizine, 200 mg three times daily, was initiated and controlled the ventricular tachycardia. However, after the dose of moricizine was titrated upward, the patient became symptomatically bradycardic and the ECG exhibited 2:1 block of her paced rhythm and an increased ventricular pacing threshold.

Asunto(s)

Antiarrítmicos/uso terapéutico; Moricizina/uso terapéutico; Marcapaso Artificial; Taquicardia Ventricular/terapia; Anciano; Electrocardiografía; Femenino; Sistema de Conducción Cardíaco/efectos de los fármacos; Sistema de Conducción Cardíaco/fisiopatología; Humanos; Taquicardia Ventricular/fisiopatología

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Marcapaso Artificial / Moricizina / Taquicardia Ventricular / Antiarrítmicos Límite: Aged / Female / Humans Idioma: En Revista: Pacing Clin Electrophysiol Año: 2003 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

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