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A summary of results of the Dietary Intervention Study in Children (DISC): lessons learned.
Van Horn, Linda; Obarzanek, Eva; Barton, Bruce A; Stevens, Victor J; Kwiterovich, Peter O; Lasser, Norman L; Robson, Alan M; Franklin, Frank A; Lauer, Ronald M; Kimm, Sue Y S; Dorgan, Joanne F; Greenlick, Merwyn R.
Afiliación
  • Van Horn L; Department of Preventive Medicine, Northwestern University Medical School, 680 North Lake Shore Drive, #1102, Chicago, IL 60611, USA. LVanhorn@Northwestern.edu
Prog Cardiovasc Nurs ; 18(1): 28-41, 2003.
Article en En | MEDLINE | ID: mdl-12624570
Prevention of cardiovascular disease must begin in childhood, preferably before risk factors develop. Elevated low-density lipoprotein cholesterol levels in children are likely to track over time and become high-risk levels in adults. The Dietary Intervention Study in Children (DISC) was a multicenter, collaborative randomized trial in pre-adolescent children designed to test the efficacy and safety of a dietary intervention to lower saturated fat and cholesterol intake among growing children with elevated low-density lipoprotein cholesterol. Numerous DISC results, which include findings on lipids-lipoproteins, genetics, and nutrient adequacy, as well as descriptions of the behavioral intervention strategies, have been reported. A summary of practical findings and their potential clinical applications have not previously been published. Highlights of key lessons learned from DISC and translational applications of potential interest to nurses and other health care providers are presented.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Grasas de la Dieta Tipo de estudio: Clinical_trials / Observational_studies / Prognostic_studies Aspecto: Equity_inequality Límite: Child / Female / Humans / Male País/Región como asunto: America do norte Idioma: En Revista: Prog Cardiovasc Nurs Asunto de la revista: ANGIOLOGIA / CARDIOLOGIA / ENFERMAGEM Año: 2003 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Grasas de la Dieta Tipo de estudio: Clinical_trials / Observational_studies / Prognostic_studies Aspecto: Equity_inequality Límite: Child / Female / Humans / Male País/Región como asunto: America do norte Idioma: En Revista: Prog Cardiovasc Nurs Asunto de la revista: ANGIOLOGIA / CARDIOLOGIA / ENFERMAGEM Año: 2003 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos