Bullous SLE: response to methotrexate and relationship with disease activity.
Lupus
; 12(1): 63-6, 2003.
Article
en En
| MEDLINE
| ID: mdl-12587829
We report on a case of 40-year-old female with systemic lupus erythematosus (SLE) who developed a severe bullous eruption on sun-exposed areas. The bullous manifestation was associated with a flare of lupus serologies, whereas the previous manifestations of the disease were quiescent. Due to prior intolerance to many drugs, she was given oral methotrexate (10 mg/week). The drug administration was followed by a rapid and full resolution of cutaneous lesions. Five months later she developed a class III lupus nephritis. Our case is the first report of efficacy of methotrexate in bullous SLE and rises the question of the relationship between bullous eruption and SLE activity.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Metotrexato
/
Enfermedades Cutáneas Vesiculoampollosas
/
Fármacos Dermatológicos
/
Lupus Eritematoso Sistémico
Límite:
Adult
/
Female
/
Humans
Idioma:
En
Revista:
Lupus
Asunto de la revista:
REUMATOLOGIA
Año:
2003
Tipo del documento:
Article
País de afiliación:
Italia
Pais de publicación:
Reino Unido