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Early-onset group B streptococcal sepsis in a preterm infant with Kostmann syndrome.
Fujiu, T; Maruyama, K; Koizumi, T.
Afiliación
  • Fujiu T; Department of Neonatology, Gunma Children's Medical Center, 779 Shimohakoda, Hokkitsu, Gunma 377-8577, Japan. tfujiu@gcmc.pref.gunma.jp
Acta Paediatr ; 91(12): 1397-9, 2002.
Article en En | MEDLINE | ID: mdl-12578301
UNLABELLED: A preterm infant died of group B streptococcal sepsis 7 h after birth. The infant's complete blood count showed total agranulocytosis. Histopathology of the major organs showed significant bacterial invasion without infiltration of polymorphonuclear leucocytes. Examination of the bone marrow revealed normal cellularity of the granulocyte precursors with arrested maturation. These findings are consistent with Kostmann syndrome. CONCLUSION: It is suggested that in patients with deteriorating early-onset infection, underlying congenital abnormalities in host defence, such as Kostmann syndrome, should be considered.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones Estreptocócicas / Streptococcus agalactiae / Agranulocitosis / Enfermedades del Prematuro Límite: Humans / Male / Newborn Idioma: En Revista: Acta Paediatr Año: 2002 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Noruega
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones Estreptocócicas / Streptococcus agalactiae / Agranulocitosis / Enfermedades del Prematuro Límite: Humans / Male / Newborn Idioma: En Revista: Acta Paediatr Año: 2002 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Noruega