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Selective precipitation of haptoglobin and alpha2-macroglobulin from human serum using Alocasia macrorhiza tuber protein.
Nayak, B Shivananda; Ulloor, N Jagadish; Shivaraj, B.
Afiliación
  • Nayak BS; Department of Biochemistry, Kasturba Medical College, Manipal-576 119, India. drbsraj@yahoo.co.in
Protein Pept Lett ; 9(6): 503-10, 2002 Dec.
Article en En | MEDLINE | ID: mdl-12553858
Treatment of human serum with ammonium sulfate fraction (0-50%) of Alocasia macrorhiza tuber extract resulted in precipitation at neutral pH. The precipitate was dissolved at pH 10.5 and chromatographed on Sephadex G-100 column. Two protein peaks were resolved. While the first peak represented alpha2-macroglobulin and haptoglobin, the second peak accounted for specific Alocasia protein. Incidentally the Alocasia protein was shown to be responsible for selective and specific precipitation of alpha2-macroglobulin and haptoglobin from serum. Thus the plant protein in its pure form or in crude stage could be used for the rapid isolation of two of the prominent alpha2-globulins.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Análisis Químico de la Sangre / Alfa-Macroglobulinas / Haptoglobinas / Alocasia Límite: Humans Idioma: En Revista: Protein Pept Lett Asunto de la revista: BIOQUIMICA Año: 2002 Tipo del documento: Article País de afiliación: India Pais de publicación: Países Bajos
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Análisis Químico de la Sangre / Alfa-Macroglobulinas / Haptoglobinas / Alocasia Límite: Humans Idioma: En Revista: Protein Pept Lett Asunto de la revista: BIOQUIMICA Año: 2002 Tipo del documento: Article País de afiliación: India Pais de publicación: Países Bajos