Lipid and carbohydrate metabolic studies after one year of megestrol acetate treatment.
Fertil Steril
; 27(2): 157-61, 1976 Feb.
Article
en En
| MEDLINE
| ID: mdl-1248663
A prospective study of lipid and carbohydrate metabolic parameters was made in 22 women who had taken a daily oral dose of 0.5 mg of megestrol acetate for contraception for 1 year. Studies of the fasting blood cholesterol and triglyceride levels demonstrated no significant change. A 3-hour oral glucose tolerance test was performed before and after 1 year of treatment. After therapy, the fasting blood glucose levels were normal but the 0.5- and 2-hour levels were elevated. All but one of the plasma insulin levels were elevated at the 1-year test. Since body weights and the fasting levels of plasma growth hormone were unchanged, they were probably not involved in the carbohydrate alteration. These results point out the need for long-term studies and the necessity for investigating the metabolic effects of all progestogen contraceptives.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Metabolismo de los Hidratos de Carbono
/
Metabolismo de los Lípidos
/
Megestrol
Tipo de estudio:
Observational_studies
Límite:
Adult
/
Female
/
Humans
Idioma:
En
Revista:
Fertil Steril
Año:
1976
Tipo del documento:
Article
Pais de publicación:
Estados Unidos