Successful treatment of familial Mediterranean fever attacks with thalidomide in a colchicine resistant patient.

Seyahi, E; Ozdogan, H; Masatlioglu, S; Yazici, H

Seyahi, E; Ozdogan, H; Masatlioglu, S; Yazici, H.

Afiliación

Seyahi E; Department of Rheumatology, Cerrahpasa Medical Faculty, University of Istanbul, Turkey.

Clin Exp Rheumatol ; 20(4 Suppl 26): S43-4, 2002.

Article en En | MEDLINE | ID: mdl-12371635

RESUMEN

Colchicine is the treatment of choice in familial Mediterranean fever (FMF) both for attacks and for prevention of secondary amyloidosis. The overall non-responder rate varies from 5-10 to 40%. Thalidomide is known to blunt the acute phase response. We report the efficacy of the addition of thalidomide to colchicine in controlling the febrile attacks and acute phase response in a patient with FMF resistant to 2 mg colchicine per day.

Asunto(s)

Colchicina/uso terapéutico; Fiebre Mediterránea Familiar/tratamiento farmacológico; Inmunosupresores/uso terapéutico; Talidomida/uso terapéutico; Quimioterapia Combinada; Humanos; Masculino; Persona de Mediana Edad

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fiebre Mediterránea Familiar / Talidomida / Colchicina / Inmunosupresores Límite: Humans / Male / Middle aged Idioma: En Revista: Clin Exp Rheumatol Año: 2002 Tipo del documento: Article País de afiliación: Turquía Pais de publicación: Italia

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