Some biochemical effects of long term oral contraceptive therapy on Egyptian females living in rural areas.
Popul Sci
; (3): 101-12, 1982.
Article
en En
| MEDLINE
| ID: mdl-12266211
PIP: The serum activity of glutamic oxaloacetic transaminase, glutamic pyruvic transaminase and alkaline phosphatase, serum nilirubin (total, direct and indirect), serum proteins (total, albumin, alpha 1, alpha 2, beta and gamma globulins), serum glycoproteins (glyco-albumin, alpha 1, alpha 2, beta and glycoglobulins) and serum lipoproteins (alpha,pre beta, beta and chylomicrons) were studied in 131 Egyptian females receiving either 1 of 2 types of oral contraceptives. These parameters were evaluated before and after 6 and 12 months of continuous use of either 1) mg lynestrenol + 0.05 mg ethinyl estradiol) or (0.5 mg lynestrenol). All these biochemical entities remained within normal limits except serum albumin which showed a significant decrease from the pretreatment level. This decrease could be attributed to a decreased rate of albumin synthesis. Since the liver is the main organ for albumin synthesis, the reduction in albumin might indicate a possible deleterious effect of the hormones on the liver. The determination of the albumin level in the serum may serve as an index to the effect of contraceptive hormones on the liver. Tables for the mean and standard deviation values of studied parameters for group 1 and group 2 before and after 6 and 12 months of continuous use of the combined pill and the minipill are included.^ieng
Palabras clave
Africa; Arab Countries; Biology; Blood Proteins--changes; Contraception; Contraceptive Agents, Female--pharmacodynamics; Contraceptive Agents, Female--side effects; Contraceptive Agents, Progestin--pharmacodynamics; Contraceptive Agents, Progestin--side effects; Contraceptive Agents--pharmacodynamics; Contraceptive Agents--side effects; Contraceptive Methods--pharmacodynamics; Contraceptive Methods--side effects; Demographic Factors; Developing Countries; Diseases; Egypt; Family Planning; Hemic System; Hepatic Effects; Liver Dysfunction; Mediterranean Countries; Northern Africa; Oral Contraceptives, Combined--pharmacodynamics; Oral Contraceptives, Combined--side effects; Oral Contraceptives, Low-dose; Oral Contraceptives--pharmacodynamics; Oral Contraceptives--side effects; Physiology; Population; Population Characteristics; Progestins, Low-dose--pharmacodynamics; Progestins, Low-dose--side effects; Research Report; Rural Population--women
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Población Rural
/
Proteínas Sanguíneas
/
Anticonceptivos Orales
/
Anticonceptivos Orales Combinados
/
Congéneres de la Progesterona
/
Hígado
/
Hepatopatías
Aspecto:
Determinantes_sociais_saude
País/Región como asunto:
Africa
/
Asia
Idioma:
En
Revista:
Popul Sci
Año:
1982
Tipo del documento:
Article
Pais de publicación:
Egipto